Cardiac Natriuretic Peptides: Contributors to Cardiac Cachexia or Possible Anti-obesity Agents or Both?
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چکیده
منابع مشابه
Cardiac Natriuretic Peptides: Contributors to Cardiac Cachexia or Possible Anti-obesity Agents or Both?
The cardiac natriuretic peptides (NPs) atrial natriuretic peptide (ANP) and B-type natriuretic peptide (BNP) are both secreted by the heart in response to myocardial stress and stretch and act via binding to guanylyl cyclase-A (GC-A), with subsequent generation of the second messenger cyclic guanosine monophosphate. GC-A is widely expressed in mammals, e.g., in heart, kidney, vascular smooth mu...
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ژورنال
عنوان ژورنال: Diabetes
سال: 2012
ISSN: 0012-1797,1939-327X
DOI: 10.2337/db12-0763